Cytokeratin 1 antibody (pan)
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- Target See all Cytokeratin 1 (KRT1) Antibodies
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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Binding Specificity
- pan
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Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Pig, Avian, Hamster
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cytokeratin 1 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognizes keratin Species Reactivity: Most mammals and birds.
- Immunogen
- Keratin extracted from human skin. Antigen Location: Cytoplasm
- Top Product
- Discover our top product KRT1 Primary Antibody
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- Application Notes
- Immunohistochemistry - Frozen sections: Fixation for 3 min. with 1% formaldehyde is recommended. Formaldehyde-fixed, paraffin-embedded tissue sections: Proteolytic pretreatment with pronase or trypsine is recommended. Use at a 1:50 dilution in PBS or Tris. Recommended positive control: Squamous cell carcinoma, skin, cervix. The optimal dilution for a specific application should be determined by the researcher.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.25 mL affinity chromatography purified liquid antiserum.
- Storage
- 4 °C
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- Target
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
- Alternative Name
- Cytokeratin (KRT1 Products)
- Synonyms
- CK1 antibody, EHK antibody, EHK1 antibody, EPPK antibody, K1 antibody, KRT1A antibody, NEPPK antibody, Krt-2.1 antibody, Krt2-1 antibody, Krt86 antibody, KRT1 antibody, Kb1 antibody, KER1 antibody, CK-1 antibody, Keratin-1 antibody, keratin 1 antibody, KRT1 antibody, Krt1 antibody
- Background
- This polyclonal antibody reacts with keratin of most mammals and birds. A positive reaction is obtained with all stratified squamous epithelia and in epidermal appendages such as hairfollicles and sebaceous glands. Also the epithelia of the urinary tract, stomach, small and large intestine, uterine endometrium, bile ducts, prostate, kidney collecting tubules, thymic reticulum cells, mesothelium and to a lesser extent hepatocytes, adenocarcinomas, transitional cell carcinomas and anaplastic carcinomas can be identified by this antiserum. Renal cell adenocarcinomas and small cell anaplastic lung tumors may remain negative when examined in paraffin sections. Hepatocytes and pancreatic acini show a positive staining. Nearly all cultured epithelial cells are positive, all non-epithelial cells are negative.
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